Read our prediction for England vs Spain below. This preview was written by a sport journalist who is specialised in betting tips and predictions.
England vs Spain Prediction & Betting tips
England and Spain face off on Saturday, September 26, 2026, at Wembley Stadium in London, in the opening-round showdown of the new UEFA Nations League season (League A, Group 3). The match is a rematch of the Euro 2024 final and a high-stakes clash between two of the strongest teams of the moment. England leads the overall head-to-head record with 14 wins in 28 encounters, compared to Spain’s 11. However, in recent times (since 2000), Spain has dominated with 6 wins to England’s 3. Spain defeated England 2-1 in the Euro 2024 final in Berlin, thanks to a late goal scored by Mikel Oyarzabal.
England:
Under the management of Thomas Tuchel, England is beginning a new cycle after securing the bronze medal at the World Cup—finishing third following a spectacular 6-4 victory over France. Tuchel is already facing squad issues, with five players unavailable due to injury (including Spence, James, and Livramento). In attack, Harry Kane remains the key figure, supported by Dominic Calvert-Lewin’s excellent club form and the creativity of Jude Bellingham and Cole Palmer.
England (4-2-3-1): Jordan Pickford – Trent Alexander-Arnold (or Jarell Quansah), Ezri Konsa, Marc Guéhi, Nico O’Reilly – Elliot Anderson, Alex Scott (or Morgan Gibbs-White) – Bukayo Saka, Jude Bellingham, Anthony Gordon – Harry Kane.
Spain:
Spain arrives in London as the reigning world and European champion. The squad led by Luis de la Fuente won the 2026 World Cup this summer—following a 1–0 victory over Argentina—and boasts an incredible streak of 38 consecutive matches without a defeat in regulation time. De la Fuente is relying on the core group that delivered global success. Key players such as Fabián Ruiz (who boasts an unbeaten record across 50 caps) and Ferran Torres are ready to maintain the Spanish side’s rhythm, built on possession and rapid transitions.
Spain (4-3-3): Unai Simón – Eric García, Pau Cubarsí, Aymeric Laporte, Marc Cucurella – Rodri, Pedri, Dani Olmo – Lamine Yamal, Mikel Oyarzabal (or Ferran Torres), Nico Williams.
England vs Spain head to head matches
14.07.2024 Spain – England 2:1
15.10.2018 Spain – England 2:3
08.09.2018 England – Spain 1:2
15.11.2016 England – Spain 2:2
13.11.2015 Spain – England 2:0
* Our advice is: BTS / YES
* Selection odd for this bet is: 1.67
* This analyis is from our perspective and we highly recommend to inform also yourself about all details that can be decisive in your choise to bet!